Plasma cathepsin D activity is negatively associated with hepatic insulin sensitivity in overweight and obese humans

AIMS/HYPOTHESIS: Insulin resistance in skeletal muscle and liver plays a major role in the pathophysiology of type 2 diabetes. The hyperinsulinaemic–euglycaemic clamp is considered the gold standard for assessing peripheral and hepatic insulin sensitivity, yet it is a costly and labour-intensive pro...

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Vydáno v:Diabetologia
Hlavní autoři: Ding, Lingling, Goossens, Gijs H., Oligschlaeger, Yvonne, Houben, Tom, Blaak, Ellen E., Shiri-Sverdlov, Ronit
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6946744/
https://ncbi.nlm.nih.gov/pubmed/31690989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-019-05025-2
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