Inhibiting Extracellular Cathepsin D Reduces Hepatic Steatosis in Sprague–Dawley Rats †

Dietary and lifestyle changes are leading to an increased occurrence of non-alcoholic fatty liver disease (NAFLD). Using a hyperlipidemic murine model for non-alcoholic steatohepatitis (NASH), we have previously demonstrated that the lysosomal protease cathepsin D (CTSD) is involved with lipid dysre...

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Veröffentlicht in:Biomolecules
Hauptverfasser: Khurana, Princy, Yadati, Tulasi, Goyal, Sandeep, Dolas, Atul, Houben, Tom, Oligschlaeger, Yvonne, Agarwal, Anil K., Kulkarni, Aditya, Shiri-Sverdlov, Ronit
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6571693/
https://ncbi.nlm.nih.gov/pubmed/31060228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9050171
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