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Selecting likely causal risk factors from high-throughput experiments using multivariable Mendelian randomization

Modern high-throughput experiments provide a rich resource to investigate causal determinants of disease risk. Mendelian randomization (MR) is the use of genetic variants as instrumental variables to infer the causal effect of a specific risk factor on an outcome. Multivariable MR is an extension of...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Zuber, Verena, Colijn, Johanna Maria, Klaver, Caroline, Burgess, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6946691/
https://ncbi.nlm.nih.gov/pubmed/31911605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13870-3
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