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Primary cilia deficiency in neural crest cells models anterior segment dysgenesis in mouse

Defects affecting tissues of the anterior segment (AS) of the eye lead to a group of highly debilitating disorders called Anterior Segment Dysgenesis (ASD). Despite the identification of some causative genes, the pathogenesis of ASD remains unclear. Interestingly, several ciliopathies display condit...

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Publicat a:eLife
Autors principals: Portal, Céline, Rompolas, Panteleimos, Lwigale, Peter, Iomini, Carlo
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6946567/
https://ncbi.nlm.nih.gov/pubmed/31845891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.52423
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