APOE ε4, white matter hyperintensities, and cognition in Alzheimer and Lewy body dementia

OBJECTIVE: To determine if APOE ε4 influences the association between white matter hyperintensities (WMH) and cognitive impairment in Alzheimer disease (AD) and dementia with Lewy bodies (DLB). METHODS: A total of 289 patients (AD = 239; DLB = 50) underwent volumetric MRI, neuropsychological testing...

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Gepubliceerd in:Neurology
Hoofdauteurs: Mirza, Saira Saeed, Saeed, Usman, Knight, Jo, Ramirez, Joel, Stuss, Donald T., Keith, Julia, Nestor, Sean M., Yu, Di, Swardfager, Walter, Rogaeva, Ekaterina, St. George Hyslop, Peter, Black, Sandra E., Masellis, Mario
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Lippincott Williams & Wilkins 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6946485/
https://ncbi.nlm.nih.gov/pubmed/31575706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000008377
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