Polyphyllin I induces cell cycle arrest in prostate cancer cells via the upregulation of IL6 and P21 expression

BACKGROUND: Polyphyllin I has been reported to possess anticancer properties in various cancer types, including prostate cancer. However, little is known about the potential of Polyphyllin I in induction of prostate cancer cell cycle arrest and its underlying mechanisms. METHODS: The anti-proliferat...

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Veröffentlicht in:Medicine (Baltimore)
Hauptverfasser: Zhang, Denglu, Liu, Shuai, Liu, Zhiyong, Ma, Chenchen, Jiang, Yuehua, Sun, Chao, Li, Kailin, Cao, Guangshang, Lin, Zhaomin, Wang, Peng, Zhang, Jianye, Xu, Dawei, Kong, Feng, Zhao, Shengtian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wolters Kluwer Health 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6946393/
https://ncbi.nlm.nih.gov/pubmed/31689825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000017743
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