Clustered CTCF binding is an evolutionary mechanism to maintain topologically associating domains

BACKGROUND: CTCF binding contributes to the establishment of a higher-order genome structure by demarcating the boundaries of large-scale topologically associating domains (TADs). However, despite the importance and conservation of TADs, the role of CTCF binding in their evolution and stability rema...

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Publicado en:Genome Biol
Autores principales: Kentepozidou, Elissavet, Aitken, Sarah J., Feig, Christine, Stefflova, Klara, Ibarra-Soria, Ximena, Odom, Duncan T., Roller, Maša, Flicek, Paul
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6945661/
https://ncbi.nlm.nih.gov/pubmed/31910870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-019-1894-x
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