Toll-like receptor 4 agonist and antagonist lipopolysaccharides modify innate immune response in rat brain circumventricular organs

BACKGROUND: The circumventricular organs (CVOs) are blood-brain-barrier missing structures whose activation through lipopolysaccharide (LPS) is a starting point for TLR-driven (Toll-like receptors) neuroinflammation. The aim of this study was to evaluate in the CVO area postrema (AP), subfornical or...

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Bibliografiske detaljer
Udgivet i:J Neuroinflammation
Main Authors: Vargas-Caraveo, Alejandra, Sayd, Aline, Robledo-Montaña, Javier, Caso, Javier R., Madrigal, José L. M., García-Bueno, Borja, Leza, Juan C.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6945636/
https://ncbi.nlm.nih.gov/pubmed/31906991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1690-2
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