Origin and consequences of brain Toll-like receptor 4 pathway stimulation in an experimental model of depression

BACKGROUND: There is a pressing need to identify novel pathophysiological pathways relevant to depression that can help to reveal targets for the development of new medications. Toll-like receptor 4 (TLR-4) has a regulatory role in the brain's response to stress. Psychological stress may compro...

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Autori principali: Gárate, Iciar, García-Bueno, Borja, Madrigal, José LM, Bravo, Lidia, Berrocoso, Esther, Caso, Javier R, Micó, Juan A, Leza, Juan C
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219571/
https://ncbi.nlm.nih.gov/pubmed/22053929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-151
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