Malignant transformation of oral leukoplakia is associated with macrophage polarization

BACKGROUND: Most oral squamous cell carcinomas (OSCC) occur on the basis of oral leukoplakias (OLP). The histologic degree of dysplasia is insufficient for the prediction of OLP malignant transformation. Immunologic parameters are gaining importance for prognostic assessment and therapy of cancer. M...

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Publicat a:J Transl Med
Autors principals: Weber, Manuel, Wehrhan, Falk, Baran, Christoph, Agaimy, Abbas, Büttner-Herold, Maike, Öztürk, Hatice, Neubauer, Kristina, Wickenhauser, Claudia, Kesting, Marco, Ries, Jutta
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6945578/
https://ncbi.nlm.nih.gov/pubmed/31910881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-02191-0
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