Malignant transformation of oral leukoplakia is associated with macrophage polarization

BACKGROUND: Most oral squamous cell carcinomas (OSCC) occur on the basis of oral leukoplakias (OLP). The histologic degree of dysplasia is insufficient for the prediction of OLP malignant transformation. Immunologic parameters are gaining importance for prognostic assessment and therapy of cancer. M...

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Bibliografiske detaljer
Udgivet i:J Transl Med
Main Authors: Weber, Manuel, Wehrhan, Falk, Baran, Christoph, Agaimy, Abbas, Büttner-Herold, Maike, Öztürk, Hatice, Neubauer, Kristina, Wickenhauser, Claudia, Kesting, Marco, Ries, Jutta
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6945578/
https://ncbi.nlm.nih.gov/pubmed/31910881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-02191-0
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