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Malignant transformation of oral leukoplakia is associated with macrophage polarization

BACKGROUND: Most oral squamous cell carcinomas (OSCC) occur on the basis of oral leukoplakias (OLP). The histologic degree of dysplasia is insufficient for the prediction of OLP malignant transformation. Immunologic parameters are gaining importance for prognostic assessment and therapy of cancer. M...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Weber, Manuel, Wehrhan, Falk, Baran, Christoph, Agaimy, Abbas, Büttner-Herold, Maike, Öztürk, Hatice, Neubauer, Kristina, Wickenhauser, Claudia, Kesting, Marco, Ries, Jutta
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6945578/
https://ncbi.nlm.nih.gov/pubmed/31910881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-02191-0
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