Therapeutic drug monitoring of infliximab compared to standard clinical treatment with infliximab: study protocol for a randomised, controlled, open, parallel-group, phase IV study (the NOR-DRUM study)

BACKGROUND: Infliximab (INX) and other tumour necrosis factor inhibitors (TNFi) have revolutionised the treatment of several immune mediated inflammatory diseases. Still, many patients do not respond sufficiently to therapy or lose efficacy over time. The large interindividual variation in serum dru...

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Bibliografiske detaljer
Udgivet i:Trials
Main Authors: Syversen, Silje W, Goll, Guro L, Jørgensen, Kristin K, Olsen, Inge C, Sandanger, Øystein, Gehin, Johanna E, Warren, David J, Sexton, Joseph, Mørk, Cato, Jahnsen, Jørgen, Kvien, Tore K, Bolstad, Nils, Haavardsholm, Espen A
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Study Protocol
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6945422/
https://ncbi.nlm.nih.gov/pubmed/31907007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-019-3734-4
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