Evaluation of antiviral - passive - active immunization (“sandwich”) therapeutic strategy for functional cure of chronic hepatitis B in mice

BACKGROUND: Chronic Hepatitis B (CHB) remains a major problem for global public health. Viral persistence and immune defects are the two major reasons for CHB, and it was hypothesized that based on a transient clearance of serum viral DNA and HBsAg “window stage”, active immunization against hepatit...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Shi, Bisheng, Wu, Yanling, Wang, Chunyu, Li, Xiaofang, Yu, Fan, Wang, Bin, Yang, Zhenlin, Li, Jianhua, Liang, Mifang, Wen, Yumei, Ying, Tianlei, Yuan, Zhenghong
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6945269/
https://ncbi.nlm.nih.gov/pubmed/31680000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.10.043
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