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Dioscin ameliorates peritoneal fibrosis by inhibiting epithelial-to-mesenchymal transition of human peritoneal mesothelial cells via the TLR4/MyD88/NF-κB signaling pathway

Objective: To investigate the effect of dioscin on lipopolysaccharide (LPS)-induced peritoneal fibrosis and its underlying mechanism. Methods: The human peritoneal mesothelial cell line (HMrSV5) was treated with LPS, followed by treatment with different concentrations of dioscin (0.25, 0.5 or 1.0 μg...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Pathol
Main Authors: Shao, Qiuyuan, Jiang, Chunming, Xia, Yangyang, Zhao, Min, Zhang, Qingyan, Jin, Bo, Liu, Jin
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6945188/
https://ncbi.nlm.nih.gov/pubmed/31933895
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