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Dioscin alleviates alcoholic liver fibrosis by attenuating hepatic stellate cell activation via the TLR4/MyD88/NF-κB signaling pathway

The present work aimed to investigate the activities and underlying mechanisms of dioscin against alcoholic liver fibrosis (ALF). In vivo liver fibrosis in mice was induced by an alcoholic liquid diet, and in vitro studies were performed on activated HSC-T6 and LX2 cells treated with lipopolysacchar...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Liu, Min, Xu, Youwei, Han, Xu, Yin, Lianhong, Xu, Lina, Qi, Yan, Zhao, Yanyan, Liu, Kexin, Peng, Jinyong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674875/
https://ncbi.nlm.nih.gov/pubmed/26655640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18038
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