Identification of a transient state during the acquisition of temozolomide resistance in glioblastoma

Drug resistance limits the therapeutic efficacy in cancers and leads to tumor recurrence through ill-defined mechanisms. Glioblastoma (GBM) are the deadliest brain tumors in adults. GBM, at diagnosis or after treatment, are resistant to temozolomide (TMZ), the standard chemotherapy. To better unders...

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Опубликовано в: :Cell Death Dis
Главные авторы: Rabé, Marion, Dumont, Solenne, Álvarez-Arenas, Arturo, Janati, Hicham, Belmonte-Beitia, Juan, Calvo, Gabriel F., Thibault-Carpentier, Christelle, Séry, Quentin, Chauvin, Cynthia, Joalland, Noémie, Briand, Floriane, Blandin, Stéphanie, Scotet, Emmanuel, Pecqueur, Claire, Clairambault, Jean, Oliver, Lisa, Perez-Garcia, Victor, Nadaradjane, Arulraj, Cartron, Pierre-François, Gratas, Catherine, Vallette, François M.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944699/
https://ncbi.nlm.nih.gov/pubmed/31907355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-2200-2
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