Specific Inhibition of DNMT3A/ISGF3γ Interaction Increases the Temozolomide Efficiency to Reduce Tumor Growth

DNA methylation is a fundamental feature of genomes and is a candidate for pharmacological manipulation that might have important therapeutic advantage. Thus, DNA methyltransferases (DNMTs) appear to be ideal targets for drug intervention. By focusing on interactions existing between DNMT3A and DNMT...

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Veröffentlicht in:Theranostics
Hauptverfasser: Cheray, Mathilde, Pacaud, Romain, Nadaradjane, Arulraj, Oliver, Lisa, Vallette, François M, Cartron, Pierre-François
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039338/
https://ncbi.nlm.nih.gov/pubmed/27698935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.9150
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