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Validation and implementation of an ultrasensitive liquid chromatographic-tandem mass spectrometric (LC-MS/MS) assay for dapivirine quantitation in breast milk

BACKGROUND: The non-nucleoside reverse transcriptase inhibitor dapivirine has been evaluated as a topical microbicidal agent to prevent HIV-1 acquisition. Several clinical trials have evaluated the pharmacokinetics of dapivirine when administered as a 25-mg intravaginal ring. Recent studies have foc...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Clin Biochem
Main Authors: Manohar, Madhuri, Marzinke, Mark A.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944438/
https://ncbi.nlm.nih.gov/pubmed/31843664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clinbiochem.2019.12.005
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