The Driver of Extreme Human-Specific Olduvai Repeat Expansion Remains Highly Active in the Human Genome

Sequences encoding Olduvai protein domains (formerly DUF1220) show the greatest human lineage-specific increase in copy number of any coding region in the genome and have been associated, in a dosage-dependent manner, with brain size, cognitive aptitude, autism, and schizophrenia. Tandem intragenic...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Genetics
Päätekijät: Heft, Ilea E., Mostovoy, Yulia, Levy-Sakin, Michal, Ma, Walfred, Stevens, Aaron J., Pastor, Steven, McCaffrey, Jennifer, Boffelli, Dario, Martin, David I., Xiao, Ming, Kennedy, Martin A., Kwok, Pui-Yan, Sikela, James M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Genetics Society of America 2020
Aiheet:
Investigations
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944415/
https://ncbi.nlm.nih.gov/pubmed/31754017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.119.302782
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia