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The Driver of Extreme Human-Specific Olduvai Repeat Expansion Remains Highly Active in the Human Genome
Sequences encoding Olduvai protein domains (formerly DUF1220) show the greatest human lineage-specific increase in copy number of any coding region in the genome and have been associated, in a dosage-dependent manner, with brain size, cognitive aptitude, autism, and schizophrenia. Tandem intragenic...
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| Publicado no: | Genetics |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6944415/ https://ncbi.nlm.nih.gov/pubmed/31754017 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.119.302782 |
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