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The Karyopherin proteins, Crm1 and Karyopherin β1, are overexpressed in cervical cancer and are critical for cancer cell survival and proliferation

The Karyopherin proteins are involved in nucleo-cytoplasmic trafficking and are critical for protein and RNA subcellular localization. Recent studies suggest they are important in nuclear envelope component assembly, mitosis and replication. Since these are all critical cellular functions, alteratio...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: van der Watt, Pauline J., Maske, Christopher P., Hendricks, Denver T., Parker, M. Iqbal, Denny, Lynette, Govender, Dhirendra, Birrer, Michael J., Leaner, Virna D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944291/
https://ncbi.nlm.nih.gov/pubmed/19117056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.24146
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