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Overexpression of Kpnβ1 and Kpnα2 Importin Proteins in Cancer Derives from Deregulated E2F Activity

The Karyopherin superfamily comprises nuclear transport proteins, involved in the shuttling of certain cargo proteins into and out of the nucleus. Karyopherin β1 (Kpnβ1) and Karyopherin α2 (Kpnα2) are importin proteins, which work in concert to transport their cargo into the nucleus. We previously i...

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Detalhes bibliográficos
Main Authors: van der Watt, Pauline J., Ngarande, Ellen, Leaner, Virna D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220698/
https://ncbi.nlm.nih.gov/pubmed/22125623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027723
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