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TGF-β1 induces airway smooth muscle cell proliferation and remodeling in asthmatic mice by up-regulating miR-181a and suppressing PTEN

Several studies have shown that transforming growth factor β1 (TGF-β1) plays a crucial role in remodeling and proliferation of airway smooth muscle cells (ASMCs). However, its molecular mechanism needs to be further studied. TGF-β1 can up-regulate the level of miR-181a in multiple cells, while miR-1...

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Detalles Bibliográficos
Publicado en:Int J Clin Exp Pathol
Main Authors: Lv, Xianghong, Li, Yan, Gong, Qi, Jiang, Zhong
Formato: Artigo
Idioma:Inglês
Publicado: e-Century Publishing Corporation 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944012/
https://ncbi.nlm.nih.gov/pubmed/31933731
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