MiRNA‐620 promotes TGF‐β1‐induced proliferation of airway smooth muscle cell through controlling PTEN/AKT signaling pathway

Abstract Asthma is an inflammatory syndrome characterized by airway hyperresponsiveness, bronchial inflammation, and airway remodeling. The hypertrophy and hyperplasia of airway smooth muscle cells (ASMCs) are hallmarks of bronchial remodeling in asthma. In this study, the regulatory effects of micr...

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Detalhes bibliográficos
Main Authors: Hui Chen, Su‐Xiang Guo, Sai Zhang, Xiao‐Dan Li, Hao Wang, Xiao‐Wei Li
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2020-11-01
Colecção:Kaohsiung Journal of Medical Sciences
Assuntos:
airway smooth muscle cell (ASMC)
microRNA‐620 (miR‐620)
phosphatase and tensin homolog (PTEN)
protein kinase B (AKT)
transforming growth factor‐β1 (TGF‐β1)
Acesso em linha:https://doi.org/10.1002/kjm2.12260
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