Blood biomarkers as surrogate endpoints of treatment responses to aerobic exercise and cognitive training (ACT) in amnestic mild cognitive impairment: the blood biomarkers study protocol of a randomized controlled trial (the ACT Trial)

BACKGROUND: Alzheimer’s disease (AD) is an epidemic with tremendous public health impacts because there are currently no disease-modifying therapeutics. Randomized controlled trials (RCTs) for prevention of AD dementia often use clinical endpoints that take years to manifest (e.g., cognition) or sur...

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Bibliografske podrobnosti
izdano v:Trials
Main Authors: Li, Danni, Mielke, Michelle M., Bell, W. Robert, Reilly, Cavan, Zhang, Lin, Lin, Feng Vankee, Yu, Fang
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Study Protocol
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6943901/
https://ncbi.nlm.nih.gov/pubmed/31907024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-019-3798-1
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