Mode of action of granulocyte-colony stimulating factor (G-CSF) as a novel therapy for stroke in a mouse model

BACKGROUND: The FDA approved drug granulocyte-colony stimulating factor (G-CSF) displays anti-apoptotic and immunomodulatory properties with neurogenesis and angiogenic functions. It is known to demonstrate neuroprotective mechanisms against ischemic global stroke. Autophagy is a method for the degr...

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Detalhes bibliográficos
Publicado no:J Biomed Sci
Main Authors: Modi, Jigar, Menzie-Suderam, Janet, Xu, Hongyuan, Trujillo, Paola, Medley, Kristen, Marshall, Michael L., Tao, Rui, Prentice, Howard, Wu, Jang-Yen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6943893/
https://ncbi.nlm.nih.gov/pubmed/31907023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-019-0597-7
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