Mechanisms of Neuronal Protection against Excitotoxicity, Endoplasmic Reticulum Stress, and Mitochondrial Dysfunction in Stroke and Neurodegenerative Diseases

In stroke and neurodegenerative disease, neuronal excitotoxicity, caused by increased extracellular glutamate levels, is known to result in calcium overload and mitochondrial dysfunction. Mitochondrial deficits may involve a deficiency in energy supply as well as generation of high levels of oxidant...

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Bibliografiske detaljer
Udgivet i:Oxid Med Cell Longev
Main Authors: Prentice, Howard, Modi, Jigar Pravinchandra, Wu, Jang-Yen
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2015
Fag:
Review Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4630664/
https://ncbi.nlm.nih.gov/pubmed/26576229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/964518
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