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Synthesis and Pharmacological Evaluation of Hybrids Targeting Opioid and Neurokinin Receptors
Morphine, which acts through opioid receptors, is one of the most efficient analgesics for the alleviation of severe pain. However, its usefulness is limited by serious side effects, including analgesic tolerance, constipation, and dependence liability. The growing awareness that multifunctional lig...
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| Publicado no: | Molecules |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6943619/ https://ncbi.nlm.nih.gov/pubmed/31817441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24244460 |
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