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Common Secondary and Tertiary Structural Features of Aptamer–Ligand Interaction Shared by RNA Aptamers with Different Primary Sequences

Aptamer selection can yield many oligonucleotides with different sequences and affinities for the target molecule. Here, we have combined computational and experimental approaches to understand if aptamers with different sequences but the same molecular target share structural and dynamical features...

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Bibliografske podrobnosti
izdano v:Molecules
Main Authors: Ilgu, Muslum, Yan, Shuting, Khounlo, Ryan M., Lamm, Monica H., Nilsen-Hamilton, Marit
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6943582/
https://ncbi.nlm.nih.gov/pubmed/31835789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24244535
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