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Synthesis and Anti-Proliferative Assessment of Triazolo-Thiadiazepine and Triazolo-Thiadiazine Scaffolds

A series of triazolo-thiadiazepines 4a–k were synthesized with excellent yields using dehydrated PTSA as a catalyst in toluene. Two triazolo-thiadiazines were obtained; 8a was formed directly by reflux in ethanol, whereas, PTSA promoted the formation of 8b. The molecular structure of the formed tria...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Boraei, Ahmed T. A., Ghabbour, Hazem A., Gomaa, Mohamed S., El Ashry, El Sayed H., Barakat, Assem
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6943432/
https://ncbi.nlm.nih.gov/pubmed/31817609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24244471
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