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Synthesis of New Functionalized Indoles Based on Ethyl Indol-2-carboxylate

Successful alkylations of the nitrogen of ethyl indol-2-carboxylate were carried out using aq. KOH in acetone. The respective N-alkylated acids could be obtained without separating the N-alkylated esters by increasing the amount of KOH and water. The use of NaOMe in methanol led to transesterificati...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Boraei, Ahmed T. A., El Ashry, El Sayed H., Barakat, Assem, Ghabbour, Hazem A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6273620/
https://ncbi.nlm.nih.gov/pubmed/26978331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21030333
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