RV-59 suppresses cytoplasmic Nrf2-mediated 5-fluorouracil resistance and tumor growth in colorectal cancer

Our previous studies indicated that tumor invasion and 5-flurouracil (5-FU) resistance in colorectal cancer (CRC) was more affected by cytoplasmic localization of expressed Nrf2 (cNrf2) than by nuclear localization (nNrf2), indicating a need for novel antitumor agents to overcome 5-FU resistance and...

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Vydáno v:Am J Cancer Res
Hlavní autoři: Shen, Ching-Ju, Lin, Po-Lin, Lin, Hsiao-Ching, Cheng, Ya-Wen, Huang, Hsu-Shan, Lee, Huei
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2019
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6943352/
https://ncbi.nlm.nih.gov/pubmed/31911862
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