Glucocorticoid receptor antagonism overcomes resistance to BRAF inhibition in BRAF(V600E)-mutated metastatic melanoma

Clinical applications of glucocorticoids (GC) in Oncology are dependent on their pro-apoptotic action to treat lymphoproliferative cancers, and to alleviate side effects induced by chemotherapy and/or radiotherapy. However, the mechanism(s) by which GC may also promote tumor progression remains uncl...

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Publicat a:Am J Cancer Res
Autors principals: Estrela, José M, Salvador, Rosario, Marchio, Patricia, Valles, Soraya L, López-Blanch, Rafael, Rivera, Pilar, Benlloch, María, Alcácer, Javier, Pérez, Carlos L, Pellicer, José A, Obrador, Elena
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2019
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6943348/
https://ncbi.nlm.nih.gov/pubmed/31911848
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