Glucocorticoid Receptor Knockdown Decreases the Antioxidant Protection of B16 Melanoma Cells: An Endocrine System-Related Mechanism that Compromises Metastatic Cell Resistance to Vascular Endothelium-Induced Tumor Cytotoxicity

We previously reported an interorgan system in which stress-related hormones (corticosterone and noradrenaline), interleukin-6, and glutathione (GSH) coordinately regulate metastatic growth of highly aggressive B16-F10 melanoma cells. Corticosterone, at levels measured in tumor-bearing mice, also in...

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Hauptverfasser: Obrador, Elena, Valles, Soraya L., Benlloch, María, Sirerol, J. Antoni, Pellicer, José A., Alcácer, Javier, Coronado, Javier Alcácer-F., Estrela, José M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011753/
https://ncbi.nlm.nih.gov/pubmed/24802641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096466
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