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Intertissue Flow of Glutathione (GSH) as a Tumor Growth-promoting Mechanism: INTERLEUKIN 6 INDUCES GSH RELEASE FROM HEPATOCYTES IN METASTATIC B16 MELANOMA-BEARING MICE

B16 melanoma F10 (B16-F10) cells with high glutathione (GSH) content show high metastatic activity in vivo. An intertissue flow of GSH, where the liver is the main reservoir, can increase GSH content in metastatic cells and promote their growth. We have studied here possible tumor-derived molecular...

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Autori principali: Obrador, Elena, Benlloch, María, Pellicer, José A., Asensi, Miguel, Estrela, José M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091180/
https://ncbi.nlm.nih.gov/pubmed/21393247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.196261
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