Gemigliptin Attenuates Renal Fibrosis Through Down-Regulation of the NLRP3 Inflammasome

BACKGROUND: The hypoglycemic drugs dipeptidyl peptidase-4 (DPP-4) inhibitors have proven protective effects on diabetic kidney disease, including renal fibrosis. Although NOD-like receptor protein 3 (NLRP3) inflammasome activation is known to play an important role in the progression of renal fibros...

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Bibliographic Details
Published in:Diabetes Metab J
Main Authors: Seo, Jung Beom, Choi, Yeon-Kyung, Woo, Hye-In, Jung, Yun-A, Lee, Sungwoo, Lee, Seunghyeong, Park, Mihyang, Lee, In-Kyu, Jung, Gwon-Soo, Park, Keun-Gyu
Format: Artigo
Language:Inglês
Published: Korean Diabetes Association 2019
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6943262/
https://ncbi.nlm.nih.gov/pubmed/30877711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4093/dmj.2018.0181
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