Development and Validation of a Volumetric Absorptive Microsampling- Liquid Chromatography Mass Spectrometry Method for the Analysis of Cefepime in Human Whole Blood: Application to Pediatric Pharmacokinetic Study

Cefepime is a fourth-generation cephalosporin antibiotic with an extended spectrum of activity against many Gram-positive and Gram-negative bacteria. There is a growing need to develop sensitive, small volume assays, along with less invasive sample collection to facilitate pediatric pharmacokinetic...

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Опубликовано в: :J Pharm Biomed Anal
Главные авторы: Moorthy, Ganesh S., Vedar, Christina, Zane, Nicole R., Downes, Kevin J., Prodell, Janice L., DiLiberto, Mary Ann, Zuppa, Athena F.
Формат: Artigo
Язык:Inglês
Опубликовано: 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6943186/
https://ncbi.nlm.nih.gov/pubmed/31785929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2019.113002
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