Tunability of DNA Polymerase Stability during Eukaryotic DNA Replication

Structural and biochemical studies have revealed the basic principles of how the replisome duplicates genomic DNA, but little is known about its dynamics during DNA replication. We reconstitute the 34 proteins needed to form the S. cerevisiae replisome and show how changing local concentrations of t...

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Pubblicato in:Mol Cell
Autori principali: Lewis, Jacob S., Spenkelink, Lisanne M., Schauer, Grant D., Yurieva, Olga, Mueller, Stefan H., Natarajan, Varsha, Kaur, Gurleen, Maher, Claire, Kay, Callum, O’Donnell, Michael E., van Oijen, Antoine M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6943181/
https://ncbi.nlm.nih.gov/pubmed/31704183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.10.005
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