Diabetic microcirculatory disturbances and pathologic erythropoiesis are provoked by deposition of amyloid-forming amylin in red blood cells and capillaries

In the setting of type-2 diabetes, there are declines of structural stability and functionality of blood capillaries and red blood cells (RBCs), increasing the risk for microcirculatory disturbances. Correcting hyperglycemia is not entirely effective at reestablishing normal cellular metabolism and...

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Udgivet i:Kidney Int
Main Authors: Verma, Nirmal, Liu, Miao, Ly, Han, Loria, Analia, Campbell, Kenneth S., Bush, Heather, Kern, Philip A., Jose, Pedro A., Taegtmeyer, Heinrich, Bers, Donald M., Despa, Sanda, Goldstein, Larry B., Murray, Andrew J., Despa, Florin
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6943180/
https://ncbi.nlm.nih.gov/pubmed/31739987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2019.07.028
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