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Microsatellite instability and immune checkpoint inhibitors: toward precision medicine against gastrointestinal and hepatobiliary cancers

Recent innovations in the next-generation sequencing technologies have unveiled that the accumulation of genetic alterations results in the transformation of normal cells into cancer cells. Accurate and timely repair of DNA is, therefore, essential for maintaining genetic stability. Among various DN...

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Bibliografiske detaljer
Udgivet i:J Gastroenterol
Main Authors: Eso, Yuji, Shimizu, Takahiro, Takeda, Haruhiko, Takai, Atsushi, Marusawa, Hiroyuki
Format: Artigo
Sprog:Inglês
Udgivet: Springer Japan 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6942585/
https://ncbi.nlm.nih.gov/pubmed/31494725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00535-019-01620-7
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