Elevated HDAC activity and altered histone phospho-acetylation confer acquired radio-resistant phenotype to breast cancer cells

BACKGROUND: Poor-responsiveness of tumors to radiotherapy is a major clinical problem. Owing to the dynamic nature of the epigenome, the identification and targeting of potential epigenetic modifiers may be helpful to curb radio-resistance. This requires a detailed exploration of the epigenetic chan...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Sharda, Asmita, Rashid, Mudasir, Shah, Sanket Girish, Sharma, Ajit Kumar, Singh, Saurav Raj, Gera, Poonam, Chilkapati, Murali Krishna, Gupta, Sanjay
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6942324/
https://ncbi.nlm.nih.gov/pubmed/31900196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-019-0800-4
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