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TRIM3 Negatively Regulates Autophagy Through Promoting Degradation of Beclin1 in Ewing Sarcoma Cells

BACKGROUND AND AIM: Ewing sarcoma (ES) is an aggressive neoplasm predominantly occurring in adolescents and has a poor prognosis when metastasized. In the current study, we were aiming to investigate the function of TRIM3 in autophagy in ES cells. METHODS: The expression of TRIM3 in Ewing sarcoma ti...

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Bibliografiske detaljer
Udgivet i:Onco Targets Ther
Main Authors: Lu, Qunshan, Zhang, Yuankai, Ma, Liang, Li, Deqiang, Li, Ming, Liu, Peilai, Li, Jianmin
Format: Artigo
Sprog:Inglês
Udgivet: Dove 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6942252/
https://ncbi.nlm.nih.gov/pubmed/32021240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S219777
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