ELF4 is a target of miR-124 and promotes neuroblastoma proliferation and undifferentiated state

13-cis-retinoic acid (RA) is typically used in post-remission maintenance therapy in patients with neuroblastoma. However, side effects and recurrence are often observed. We investigated the use of miRNAs as a strategy to replace RA as promoters of differentiation. miR-124 was identified as the top...

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Vydáno v:Mol Cancer Res
Hlavní autoři: Kosti, Adam, Du, Liqin, Shivram, Haridha, Qiao, Mei, Burns, Suzanne, Garcia, Juan Gabriel, Pertsemlidis, Alexander, Iyer, Vishwanath R., Kokovay, Erzsebet, Penalva, Luiz O.F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6942226/
https://ncbi.nlm.nih.gov/pubmed/31624087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-19-0187
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