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PRC2 activates interferon-stimulated genes indirectly by repressing miRNAs in glioblastoma
Polycomb repressive complex 2 (PRC2) is a chromatin binding complex that represses gene expression by methylating histone H3 at K27 to establish repressed chromatin domains. PRC2 can either regulate genes directly through the methyltransferase activity of its component EZH2 or indirectly by regulati...
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| Veröffentlicht in: | PLoS One |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6742368/ https://ncbi.nlm.nih.gov/pubmed/31513636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0222435 |
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