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Searching for Small Molecules with an Atomic Sort

The discovery of biologically active small molecules requires sifting through large amounts of data to identify unique or unusual arrangements of atoms. Here, we develop, test and evaluate an atom-based sort to identify novel features of secondary metabolites and demonstrate its use to evaluate nove...

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Publicado en:Angew Chem Int Ed Engl
Autores principales: Duggan, Brendan M., Cullum, Reiko, Fenical, William, Amador, Luis A., Rodríguez, Abimael D., La Clair, James J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6942196/
https://ncbi.nlm.nih.gov/pubmed/31696595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201911862
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