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A20 at the Crossroads of Cell Death, Inflammation, and Autoimmunity
A20 is a potent anti-inflammatory protein, acting by inhibiting nuclear factor κB (NF-κB) signaling and inflammatory gene expression and/or by preventing cell death. Mutations in the A20/TNFAIP3 gene have been associated with a plethora of inflammatory and autoimmune pathologies in humans and in mic...
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Publicado no: | Cold Spring Harb Perspect Biol |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
2020
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6942121/ https://ncbi.nlm.nih.gov/pubmed/31427375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a036418 |
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