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Accurate quantification of circular RNAs identifies extensive circular isoform switching events

Detection and quantification of circular RNAs (circRNAs) face several significant challenges, including high false discovery rate, uneven rRNA depletion and RNase R treatment efficiency, and underestimation of back-spliced junction reads. Here, we propose a novel algorithm, CIRIquant, for accurate c...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Zhang, Jinyang, Chen, Shuai, Yang, Jingwen, Zhao, Fangqing
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941955/
https://ncbi.nlm.nih.gov/pubmed/31900416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13840-9
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