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Accurate quantification of circular RNAs identifies extensive circular isoform switching events
Detection and quantification of circular RNAs (circRNAs) face several significant challenges, including high false discovery rate, uneven rRNA depletion and RNase R treatment efficiency, and underestimation of back-spliced junction reads. Here, we propose a novel algorithm, CIRIquant, for accurate c...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6941955/ https://ncbi.nlm.nih.gov/pubmed/31900416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13840-9 |
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