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Citrus polymethoxyflavones attenuate metabolic syndrome by regulating gut microbiome and amino acid metabolism

Metabolic syndrome (MetS) is intricately linked to dysregulation of gut microbiota and host metabolomes. Here, we first find that a purified citrus polymethoxyflavone-rich extract (PMFE) potently ameliorates high-fat diet (HFD)–induced MetS, alleviates gut dysbiosis, and regulates branched-chain ami...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Zeng, Su-Ling, Li, Shang-Zhen, Xiao, Ping-Ting, Cai, Yuan-Yuan, Chu, Chu, Chen, Bai-Zhong, Li, Ping, Li, Jing, Liu, E-Hu
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941918/
https://ncbi.nlm.nih.gov/pubmed/31922003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aax6208
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