Citrus polymethoxyflavones attenuate metabolic syndrome by regulating gut microbiome and amino acid metabolism

Metabolic syndrome (MetS) is intricately linked to dysregulation of gut microbiota and host metabolomes. Here, we first find that a purified citrus polymethoxyflavone-rich extract (PMFE) potently ameliorates high-fat diet (HFD)–induced MetS, alleviates gut dysbiosis, and regulates branched-chain ami...

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Vydáno v:Sci Adv
Hlavní autoři: Zeng, Su-Ling, Li, Shang-Zhen, Xiao, Ping-Ting, Cai, Yuan-Yuan, Chu, Chu, Chen, Bai-Zhong, Li, Ping, Li, Jing, Liu, E-Hu
Médium: Artigo
Jazyk:Inglês
Vydáno: American Association for the Advancement of Science 2020
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941918/
https://ncbi.nlm.nih.gov/pubmed/31922003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aax6208
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