Stick-slip dynamics of cell adhesion triggers spontaneous symmetry breaking and directional migration of mesenchymal cells on one-dimensional lines

Directional cell motility relies on the ability of single cells to establish a front-rear polarity and can occur in the absence of external cues. The initiation of migration has often been attributed to the spontaneous polarization of cytoskeleton components, while the spatiotemporal evolution of ce...

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Veröffentlicht in:Sci Adv
Hauptverfasser: Hennig, K., Wang, I., Moreau, P., Valon, L., DeBeco, S., Coppey, M., Miroshnikova, Y. A., Albiges-Rizo, C., Favard, C., Voituriez, R., Balland, M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Association for the Advancement of Science 2020
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Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941913/
https://ncbi.nlm.nih.gov/pubmed/31921998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aau5670
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